Expression and Significance of Toll-Like Receptor 1 and Toll-Like Receptor 3 in Renal Tissues of Children with Primary Nephrotic Syndrome

To explore the expression and clinical significance of toll-like receptor 1 3 in renal tissues children with primary nephrotic syndrome. A total 120 syndrome kidney who underwent biopsy were selected as observation group, which can be divided into minimal change disease type (40 cases), membranous nephropathy (20 mesangial proliferative glomerulonephritis (30 cases) focal segmental glomerulosclerosis cases). In addition, normal 20 Wilms tumor admitted to same period control group immunohistochemistry was used. The method used detect levels two groups. Compared different pathological types had higher tubular tissues. significantly than those other groups, followed by nephropathy. type, difference statistically significant (all p<0.05). groups Toll-like have high their certain differences types.